Research Grants

cancer research grants

Driving Breakthroughs in Precision Oncology

Stage4Hope donates all funds remaining after essential operating costs each year directly to cancer research. These dollars are awarded as grants of $100,000 or more to leading investigators at top cancer centers whose work can quickly translate into better treatments for patients.

Current Focus Areas

Precision Oncology

Putting the right drug in the right patient at the right time.

Targeted Therapies

Advancing next-generation inhibitors and antibody-drug conjugates for ROS1, ALK, RET, TRK, EGFR, and other gene-driven cancers.

Lung Cancer Priority

Addressing unmet needs in advanced non-small cell lung cancer, especially ROS1-positive disease.

Clinical Trial Acceleration

Expanding access to early-phase clinical trials at leading centers.

Partnership Highlight: Memorial Sloan Kettering (MSK)

Memorial Sloan Kettering Cancer Center

Stage4Hope is proud to partner with Dr. Alex Drilon, Chief of MSK’s Early Drug Development Service, a global leader in fusion-driven lung cancer research.

Together, we are funding a $2.5 million, three-year initiative to study resistance in ROS1-positive lung cancers, expand patient-derived models, and test new therapies.

This project is designed to:

  • Uncover how cancer genes and proteins change in response to treatment.
  • Develop strategies to delay or overcome resistance to targeted therapies.
  • Build a library of patient-derived models (xenografts and organoids) to accelerate drug discovery.

Application Process

Stage4Hope currently awards research grants on a strategic, invitation-only basis, reviewed and approved by our Board with guidance from external experts.

Our vision is to expand this program to fund a growing number of transformative projects every year.

How You Can Help

  • Give to Research

    Every gift helps fuel $100,000+ investigator grants.

  • Partner With Us

    Donors can direct major gifts toward groundbreaking projects at top cancer centers.

  • Build the Future

    With your support, Stage4Hope can expand the number of grants awarded each year and accelerate breakthroughs.