Innovations Bring Hope to Lung Patients
New Lung Cancer Innovations Offering Hope to Patients
At Memorial Sloan Kettering, cutting-edge lung cancer care is changing lives—especially for those with advanced disease. Take Jen Cosgrove, a mother diagnosed with stage 4 lung cancer that had spread. Thanks to precise testing, doctors found her tumor had an ALK gene mutation, which responds well to targeted therapy called alectinib. Jen saw dramatic improvements within days and has been able to share important milestones with her children she once feared missing. MSK’s expert care, innovative treatments, and thorough diagnostics give patients like Jen hope and more time with their loved ones.
New Discoveries in Lung Cancer Detection
MSK researchers are also uncovering new types of lung cancer and better ways to detect it early. For example, they identified a rare form called atypical small cell lung carcinoma in younger patients who never smoked. Early detection remains critical, and MSK is developing noninvasive tools like the “E-nose,” a device that detects cancer-related chemicals in breath, which could make screening easier and less stressful. Lab studies on lung stem cells and tumor growth help scientists understand how cancer starts and grows, leading to better treatments. For patients facing lung cancer, these advances mean earlier diagnosis, more personalized care, and brighter hope for the future. (Source: Memorial Sloan Kettering)
Read the complete article here >
Resources for Living With Stage 4 Cancer
Learn more about topics like lung cancer innovations. Become a member of our community to gain access to trusted resources, as well as online support and education from Dr. Sharon May, Ph.D., LMFT.
Wendy’s Lung Cancer Diagnosis
Living Strong With Lung Cancer: Wendy’s ROS1-Positive Story
Wendy Lassen Feldman’s lung cancer diagnosis came after she insisted on scans despite her doctor’s initial doubts. Diagnosed in 2016 with stage 3 ROS1-positive lung cancer, Wendy faced her treatment with hope and determination. She underwent chemotherapy, radiation, and surgery—all while maintaining her daily routines and fighting to stay strong for her children. Her medical team’s confidence that she would be alive in five years gave her vital encouragement during a difficult time.
Wendy’s message to others is clear: don’t give up. Lung cancer isn’t always a death sentence, and survival rates don’t define individual outcomes. She believes in embracing cancer as part of life without letting it control her. Inspired by the Lung Cancer Research Foundation’s dedication to research, Wendy actively supports their work, helping to fund advancements that bring new options and hope to lung cancer patients everywhere. (Source: Lung Cancer Research Foundation)
Resources for Living With Stage 4 Cancer
Become a member of our community to gain access to trusted resources, online support and education from Dr. Sharon May, Ph.D., LMFT, medical updates, and invitations to supportive virtual gatherings.
Maureen’s Story: Too Busy for Cancer
Maureen’s Story: “Too Busy for Cancer” With Stage 4 Lung Cancer
Maureen’s lung cancer diagnosis came unexpectedly after a routine scan. Initially diagnosed at stage 1, her cancer progressed to stage 4 in late 2021, a moment that brought deep fear given her family history. Finding she had a KRAS mutation, Maureen became active in lung cancer communities supporting research specific to her cancer type. Motivated by the limited funding for lung cancer research, she began advocating for increased support by contacting lawmakers and raising awareness through events like the Free to Breathe Walk.
Today, Maureen embraces life fully, saying she’s “too busy for cancer.” Retired alongside her husband, she looks forward to being the nurse for her daughters when they have babies — a symbol of hope and life beyond cancer. Her story highlights the power of advocacy, community, and hope in the face of stage 4 lung cancer. (Source: Lung Cancer Research Foundation)
Read the complete article here >
Resources for Living With Stage 4 Cancer
Become a member of our community to gain access to trusted resources, online support and education from Dr. Sharon May, Ph.D., LMFT, medical updates, and invitations to supportive virtual gatherings.
Tejal’s Story: Strength in the Fight
Tejal’s Stage 4 Lung Cancer Story: Strength in the Fight
When Tejal Patel was diagnosed with stage 4 lung cancer, it was a shock, especially since she never smoked and lives a healthy lifestyle. The diagnosis felt isolating, bringing confusion and stigma, as many still wrongly assume lung cancer is caused by lifestyle choices. But Tejal found determination in her fight—not just to live and watch her twin boys grow up, but also to raise awareness and break the stigma, especially for women like her in the South Asian community.
Tejal credits the Lung Cancer Research Foundation (LCRF) for vital support and hope. Through funding life-changing research, including early detection methods and new treatments, LCRF is helping improve survival and quality of life for lung cancer patients. Tejal’s story is a powerful reminder that lung cancer can affect anyone and that ongoing research and community support are essential to keep advancing care and offering hope. (Source: Lung Cancer Research Foundation)
Read the complete article here >
Resources for Living With Stage 4 Cancer
Become a member of our community to gain access to trusted resources, as well as online support and education from Dr. Sharon May, Ph.D., LMFT.
Hope from Metastasis Research
Hope from Metastasis Research: New Advances for Stage 4 Cancer
Learn how metastasis research is uncovering how cancer spreads and resists treatment, including 3D patient models and new clinical trials offering hope for stage 4 cancer.
Metastasis is when cancer spreads from the original tumor to other parts of the body, and it’s often the toughest part to treat. Researchers at Memorial Sloan Kettering are studying how these metastatic cancer cells change and adapt to survive treatments. They found that metastatic cells can “shift” their identity to better survive, which helps explain why they become harder to stop over time.
At MSK, doctors are creating patient-based 3D models to better understand lung cancer spread and to test how different treatments work. There’s also a clinical trial exploring a drug that stops cancer cells in the brain and spine from stealing iron, which they need to grow and to avoid immune attack. This research is paving the way toward treatments that are more targeted and personalized.
For patients with late-stage or metastatic cancer, these advances offer hope for longer control of the disease and, one day, new ways to stop metastasis altogether. (Source: Memorial Sloan Kettering)
Read the complete article here >
Resources for Living With Stage 4 Cancer
Learn more about topics like metastasis research, along with other important aspects of living with Stage 4 cancer. Become a member of our community to gain access to trusted resources, as well as online support and education from Dr. Sharon May, Ph.D., LMFT.
Precision Cancer Testing Brings New Hope
Precision Cancer Testing Brings New Hope for Stage 4 Cancer
At Memorial Sloan Kettering’s Center for Molecular Oncology, doctors use advanced testing to find the exact changes in a person’s cancer cells. This helps them choose treatments that specifically target those changes, giving patients a better chance at controlling their cancer. Over the past decade, tests like MSK-IMPACT® have made it possible to check for hundreds of genetic changes, even through simple blood tests, helping people with advanced or rare cancers find personalized therapies. But DNA testing doesn’t show everything, so new tests that look at how cancer cells use genes (called RNA tests) and even check all of a person’s genes (whole-genome sequencing) are coming soon. These tools aim to help patients who don’t respond to current treatments and could also guide immunotherapy, which uses the body’s immune system to fight cancer.
This kind of testing can also find inherited gene changes that increase cancer risk, helping families take steps to prevent cancer early. One inspiring example is patient Michael Wolff, a jazz pianist whose rare cancer was identified through molecular testing. Doctors found a gene mutation that led to a drug treatment which quickly stopped his symptoms and shrank his tumors. His success shows how precise testing can save lives and open the door to new treatments for cancers that were once very hard to treat. For patients with stage 4 or difficult cancers, these advances mean more hope for better, tailored care—and the chance for improved quality of life. (Source: Memorial Sloan Kettering)
Read the complete article here >
Resources for Living With Stage 4 Cancer
Learn more about topics like precision cancer testing for stage 4 cancer. Become a member of our community to gain access to trusted resources, as well as online support and education from Dr. Sharon May, Ph.D., LMFT.
Young Mom Beats Lung Cancer Odds
Young Mom Beats Lung Cancer Odds: Lauren’s Survivor Story
Just as 38-year-old Lauren was getting back into shape after becoming a new mom, her life changed overnight. A nagging pain in her neck led to scans that uncovered a mass in her lung—stage 3 lung cancer. She went from running miles to navigating CT scans and the shock of a diagnosis she never imagined. “I remember saying, ‘Am I going to make it to my daughter Elle’s second birthday?’” Lauren recalled.
Motivated by her young daughter, Lauren faced treatment head-on. She preserved her fertility, then began chemotherapy and radiation to shrink the tumors. A portion of her lung was surgically removed after a month of healing. Throughout it all, she clung to her purpose: “Elle gave me the motivation to get up and get infusions when I was feeling my worst.” Genetic testing revealed an EGFR mutation—common in nonsmokers like Lauren and a key to unlocking targeted therapy. Now, with no evidence of disease, Lauren stays vigilant with regular scans and remains a voice of hope.
“Your support literally saves lives,” she says, grateful for both friends and strangers who make research breakthroughs possible. (Source: GO2 for Lung Cancer)
Read the complete article here >
Resources for Living With Stage 4 Cancer
Learn more about topics like young mom lung cancer survivor story. Become a member of our community to gain access to trusted resources, as well as online support and education from Dr. Sharon May, Ph.D., LMFT.
When a Cough Could Be Lung Cancer
When a Cough Could Be Lung Cancer: Signs, Risks, and Next Steps
A chronic cough is often just a sign of something like a cold, allergies, or asthma — but in some cases, it may be a warning sign of lung cancer. According to lung cancer experts, including Dr. Fatemeh Ardeshir-Larijani of Emory University, a cough that lasts longer than 8 to 12 weeks, worsens over time, or comes with other symptoms like coughing up blood, chest tightness, or unexplained weight loss should not be ignored. While many types of cough can happen with lung cancer, the most common is a dry, persistent cough that doesn’t go away with typical treatments.
People with lung cancer may also experience pressure in the chest, shortness of breath, or coughing due to fluid buildup around the lungs. Treatments to ease this kind of cough vary. For some, shrinking the tumor with chemotherapy, immunotherapy, or targeted therapy helps reduce coughing. Others may need fluid drained from their lungs or use home remedies like steam, hydration, or honey to manage the symptom. While only a small number of people with a chronic cough actually have lung cancer, it’s especially important for those at high risk — such as longtime smokers — to speak with their doctor and consider annual lung cancer screenings. (Source: Verywell Health)
Read the complete article here >
Resources for Living With Stage 4 Cancer
Learn more about topics like chronic cough as a sign of lung cancer. Become a member of our community to gain access to trusted resources, as well as online support and education from Dr. Sharon May, Ph.D., LMFT.
Not Done Living
Stage 4 HER2-Positive Lung Cancer: Gary’s Story on Enhertu
When Gary W. was diagnosed with stage 4 lung cancer, his life took a sharp turn—but he never let it stop him. Married for 44 years and retired at age 59, Gary was on a dream trip with his wife visiting U.S. National Parks when a lingering cough led to a life-changing diagnosis. Doctors found tumors in both lungs and confirmed a HER2-positive mutation. Today, he is thriving on Enhertu, a drug originally designed for breast cancer, and credits his stable health, his family, and his mindset for helping him stay active and optimistic. He walks daily, handles chores, travels, and says, “I live very much like a normal person.”
Gary’s story is a powerful reminder that lung cancer is not a dead end. With better treatments and more research happening every year, there is real hope for patients—even with stage 4 disease. His advice to others: don’t give up, stay informed, and know that there are more options than ever before. “I don’t ever want to stop living,” he says. “I was determined not to let lung cancer slow me down—if anything, it’s accelerated me.”
Read the complete article here >
Resources for Living With Stage 4 Cancer
Learn more about topics like stage 4 cancer stories by becoming a member of our community. Gain access to trusted resources, as well as online support and education from Dr. Sharon May, Ph.D., LMFT.
Consider Donating to Advance Research
RET-Positive Lung Cancer Research: How Tissue Donation Helps
RET-positive lung cancer is rare, and researchers need better lab models to study it. Learn how donating tumor tissue can help create cell lines and advance targeted treatments.
RET-positive lung cancer is a rare type of cancer driven by a change in a gene called RET, which stands for “rearranged during transfection.” This gene helps control how cells grow and divide. When it fuses with another gene or mutates, it can cause cancer to grow and spread, especially in certain lung and thyroid cancers. Because RET changes are so rare, researchers don’t have enough lab models called cancer cell lines. That makes it harder to study how the cancer behaves and becomes resistant to treatment.
One powerful way patients can help is by donating tumor tissue during a biopsy or surgery. That tissue can be used to grow RET-positive cancer cells in the lab, giving scientists tools to test new treatments and develop better, more personalized options. Thanks to the generosity of several RET patients, four new cancer cell lines are now being developed. If you’re a patient, talk to your care team about donating. Your gift could move research forward and help bring better treatments to others living with RET-driven cancer. (Source: The Happy Lungs Project)
Read the complete article here >
Resources for Living With Stage 4 Cancer
Learn more about topics like RET-positive lung cancer research. Become a member of our community to gain access to trusted resources, as well as online support and education from Dr. Sharon May, Ph.D., LMFT.
Targeted Therapies Bring New Hope in Lung Cancer
New Lung Cancer Treatments Offering Hope Through Research
Recent advancements in lung cancer treatment are offering new hope, especially for those with advanced or hard-to-treat cases. Scientists are developing highly targeted drugs that focus on the unique features of each person’s cancer. These treatments aim to attack only the cancer cells—sparing healthy ones—and may reduce side effects while helping patients live longer. New tools like antibody-drug conjugates (ADCs) and bispecific antibodies are leading the way, with some early results showing success even in cases where standard chemo and immunotherapy haven’t worked well.
Some of these new drugs target specific proteins found in certain lung cancers, including those seen in both non-small cell (NSCLC) and small cell lung cancer (SCLC). Researchers are also exploring ways to combine immune-based therapies with these new targeted drugs to overcome resistance and keep the cancer from returning. While many of these treatments are still in early testing, they represent a major step toward more personalized—and more hopeful—options for lung cancer patients. (Source: Drug Target Review)
Read the complete article here >
Resources for Living With Stage 4 Cancer
Learn more about topics like Lung Cancer Treatments by becoming a member of our community. Gain access to trusted resources, as well as online support and education from Dr. Sharon May, Ph.D., LMFT.
Study Offers Hope for Women with Lung Cancer
Lung Cancer Treatment for Women: New Research Insights
A new study is exploring why some treatments don’t work as well for women with squamous cell lung cancer, a common type of non-small cell lung cancer often linked to smoking. This form of lung cancer hasn’t responded well to the newer targeted therapies that help other types of lung cancer. But researcher Dr. Milica Momcilovic is working to change that by studying how hormones like estrogen may affect treatment outcomes in women.
What is TAK228, and why is it being studied?
TAK228 (also called sapanisertib) is an investigational targeted therapy designed to block the mTOR pathway, a major growth-and-survival signaling system that many cancers rely on. It’s considered a dual mTORC1/mTORC2 inhibitor, meaning it can shut down two key “switches” within the mTOR system that help tumor cells grow and resist treatment. Researchers are studying TAK228 in lung cancer, especially squamous cell lung cancer. This subtype has fewer targeted treatment options than other forms of non-small cell lung cancer.
Her early research in lab and animal models suggests that TAK228 may affect male and female tumors differently. In mouse models of squamous cell lung cancer, TAK228 reduced tumor growth more in male mice than in female mice. Researchers think estrogen-related signaling may interfere with how female tumors respond. When researchers paired TAK228 with an anti-estrogen medication (such as letrozole, a drug used to lower estrogen levels), tumors in female mice responded better and tumor growth decreased more significantly. This could eventually lead to more personalized treatments for women with lung cancer, helping doctors choose the right therapies and improving survival and quality of life. (Source: American Lung Association)
Read the complete article here. >
Resources for Living With Stage 4 Cancer
Learn more about topics like Lung Cancer Treatments for Women by becoming a member of our community. Gain access to trusted resources, as well as online support and education from Dr. Sharon May, Ph.D., LMFT.
- « Previous
- 1
- 2
- 3
- Next »
